Beyond Atopy

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Beyond Atopy

The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom; Stochastic Systems Group, Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, Massachusetts; Microsoft Research Cambridge, Ca...

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Beyond atopy: multiple patterns of sensitization in relation to asthma in a birth cohort study.

RATIONALE The pattern of IgE response (over time or to specific allergens) may reflect different atopic vulnerabilities which are related to the presence of asthma in a fundamentally different way from current definition of atopy. OBJECTIVES To redefine the atopic phenotype by identifying latent structure within a complex dataset, taking into account the timing and type of sensitization to sp...

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Asthma and atopy

F emale sex hormones seem to have something to do with asthma and allergy. You might think this is a bit vague, but the research on this so far doesn’t merit anything stronger. Women of reproductive age are more likely to be admitted to hospital for asthma than men. Intrigued by this, people have studied the link between asthma or allergy and markers of female sex hormone levels—for example, ti...

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Atopy and Asthma

Atopy is the genetic propensity to develop an immunoglobulin E antibody response to common allergens. The most common clinical manifestations of atopy are allergic rhinitis, asthma and atopic dermatitis. Asthma is a complex disorder of the airways, involving airway hyperresponsiveness, airflow obstruction that is at least partially reversible, and inflammation of the airways. Although atopy has...

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Vitamin D and Atopy.

Theoharis C. Theoharides, MS, MPhil, PhD, MD, FAAAAI Vitamin D is primarily found in vertebrates and it is mostly responsible for calcium homeostasis and maintenance of healthy bones. Natural vitamin D is obtained from intake of fish oils and other animal sources. Interestingly, microalgae contain both pre vitamin D and active vitamin D3. In humans, vitamin D synthesis is initiated in the skin ...

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ژورنال

عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine

سال: 2010

ISSN: 1073-449X,1535-4970

DOI: 10.1164/rccm.200907-1101oc